Vibrio parahaemolyticus

January 25, 2011 at 1:33 am | Posted in Uncategorized | Leave a comment

Vibrio parahaemolyticus
From Wikipedia, the free encyclopedia Vibrio parahaemolyticus

SEM image of V. parahaemolyticus
Scientific classification
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gamma Proteobacteria
Order: Vibrionales
Family: Vibrionaceae
Genus: Vibrio
Species: V. parahaemolyticus
Binomial name
Vibrio parahaemolyticus
(Fujino et al. 1951)
Sakazaki et al. 1963

Vibrio parahaemolyticus is a curved, rod-shaped, Gram-negative bacterium found in brackish[1] saltwater, which, when ingested, causes gastrointestinal illness in humans.[1] V. parahaemolyticus is oxidase positive, facultatively aerobic, and does not form spores. Like other members of the genus Vibrio, this species is motile, with a single, polar flagellum.[2]

1 Pathogenesis
2 Epidemiology
3 Hosts
4 References
5 External links


While infection can occur via the fecal-oral route, ingestion of bacteria in raw or undercooked seafood, usually oysters, is the predominant cause the acute gastroenteritis caused by V. parahaemolyticus.[3] Wound infections also occur, but are less common than seafood-borne disease. The disease mechanism of V. parahaemolyticus infections has not been fully elucidated.[4]

Clincal isolates usually possess two pathogenicity islands (PAI), which are acquired via horizontal gene transfer. Although the pathogenicity islands have ben sequenced, the functions of many of the PAI genes have not been elucidated. Each pathogenicity island contains a genetically-distinct Type III Secretion System, which is capable of injecting virulence proteins into host cells to cause disease. Additionally, two well-characterized virulence proteins are typically found in the pathogenicity islands, the thermostable direct hemolysin gene (tdh) or the tdh-related hemolysin gene (trh). Strains possessing the hemolysins exhibit beta-hemolysis on blood agar plates.


Outbreaks tend to be concentrated along coastal regions during the summer and early fall when higher water temperatures favor higher levels of bacteria. Seafood most often implicated includes squid, mackerel, tuna, sardines, crab, shrimp, and bivalves like oysters and clams. The incubation period of ~24 hours is followed by explosive, watery diarrhea accompanied by nausea, vomiting, abdominal cramps, and sometimes fever. Vibrio parahaemolyticus symptoms typically resolve with-in 72 hours, but can persist for up to 10 days in immunocompromised individuals. As the vast majority of cases of V. parahaemolyticus food infection are self-limiting, treatment is not typically necessary. In severe cases, fluid and electrolyte replacement is indicated.

Additionally, swimming or working in affected areas can lead to infections of the eyes or ears[5] and open cuts and wounds. Following Hurricane Katrina, there were 22 vibrio wound infections 3 of which were caused by V. parahaemolyticus and 2 of these led to death.


Hosts of Vibrio parahaemolyticus include:
Clithon retropictus[6]
Nerita albicilla[6]

^ a b CDC Disease Info vibrioparahaemolyticus_g
^ a b Ryan KJ; Ray CG (editors) (2004). Sherris Medical Microbiology (4th ed.). McGraw Hill. ISBN 0-8385-8529-9.
^ Finkelstein RA (1996). Cholera, Vibrio cholerae O1 and O139, and Other Pathogenic Vibrios. In: Barron’s Medical Microbiology (Barron S et al., eds.) (4th ed.). Univ of Texas Medical Branch. (via NCBI Bookshelf) ISBN 0-9631172-1-1.
^ Baffone W, Casaroli A, Campana R, Citterio B, Vittoria E, Pierfelici L, Donelli G (2005). “‘In vivo’ studies on the pathophysiological mechanism of Vibrio parahaemolyticus TDH(+)-induced secretion”. Microb Pathog 38 (2-3): 133–7. doi:10.1016/j.micpath.2004.11.001. PMID 15748815.
^ Penland RL, Boniuk M, Wilhelmus KR (2000). “Vibrio ocular infections on the U.S. Gulf Coast”. Cornea 19 (1): 26–9. doi:10.1097/00003226-200001000-00006. PMID 10632004.
^ a b Kumazawa NH, Kato E, Takaba T, Yokota T. (August) 1988. Survival of Vibrio parahaemolyticus in two gastropod molluscs, Clithon retropictus and Nerita albicilla. Nippon Juigaku Zasshi. 50(4): 918-24.

External links
CDC Disease Info vibrioparahaemolyticus_g
FDA Bad Bug Book entry on V. parahaemolyticus

v · d · e
Infectious diseases · Bacterial diseases: Proteobacterial G− (primarily A00–A79, 001–041, 080–109)

Categories: Vibrionales


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